Post-Exposure Prophylaxis, or PEP, is a lifesaving medication that can prevent HIV infection if taken quickly after a possible exposure. Despite its importance, PEP is often misunderstood, with myths about who should use it, how it works, and how effective it is. These misconceptions can delay access and put people at unnecessary risk. In this mythbusting guide, we’ll separate fact from fiction, clarify how PEP works, and show why knowing the truth can save lives.

⚕️ 1. Myth: PEP and PrEP are the same thing.

Fact:
They’re related but different:

  • PEP (Post-Exposure Prophylaxis) is taken after a possible exposure to HIV (within 72 hours).

  • PrEP (Pre-Exposure Prophylaxis) is taken before possible exposure to prevent infection.


⏱️ 2. Myth: I can start PEP anytime after exposure.

Fact:
PEP must be started within 72 hours (3 days) after possible HIV exposure — the sooner, the better. After that window, it’s not effective.


💊 3. Myth: One or two doses of PEP is enough.

Fact:
PEP is a 28-day course of daily medication. Taking only a few pills or stopping early means it may not work.


🩸 4. Myth: PEP guarantees I won’t get HIV.

Fact:
PEP greatly reduces the risk but is not 100% effective. Starting it quickly and taking every dose correctly maximizes protection.


🧠 5. Myth: Only doctors or hospitals can access PEP.

Fact:
Many clinics, emergency rooms, and sexual health centers provide PEP. In some areas, you can also get it through pharmacies or telehealth services — but timing is critical.


💬 6. Myth: PEP is only for gay men or sex workers.

Fact:
PEP is for anyone who may have been exposed to HIV — through sex (any orientation), needle sharing, sexual assault, or occupational exposure (like a healthcare worker).


💰 7. Myth: PEP is too expensive to get.

Fact:
Many public health programs, insurance plans, and NGOs cover PEP costs. In emergencies, clinics often provide it free or at reduced cost.


💀 8. Myth: PEP has terrible side effects.

Fact:
Most people tolerate PEP well. Some experience mild symptoms (like nausea or fatigue), which usually go away. Modern PEP regimens are much easier on the body than older HIV drugs.


🧍‍♀️ 9. Myth: If the person I had sex with “looks healthy,” I don’t need PEP.

Fact:
You can’t tell if someone has HIV by appearance. If you had unprotected sex or another possible exposure and you’re unsure of their HIV status, get assessed immediately — it’s better to be safe.


🔁 10. Myth: I can use PEP as my main form of HIV prevention.

Fact:
PEP is for emergency use only, not regular prevention. If you find yourself needing PEP often, you might be a good candidate for PrEP, which is taken before exposure and provides ongoing protection.